Fascioliasis - causes, symptoms, diagnosis and treatment

Fasciolosis - Parasitic infestation caused by liver fluke or a giant, and is characterized by a primary lesion of the hepatobiliary system. Current fastcioleza accompanied by malaise, fever, urticaria, nausea, pain in the right upper quadrant, enlarged liver, jaundice. In the diagnosis of fascioliasis informative serological methods (ELISA, IFA, RIGA), a study of duodenal contents and feces on eggs of helminths, ultrasound of the liver and biliary tract. In the complex treatment of fascioliasis include diet, intake of anthelmintics (triclabendazole, praziquantel), choleretic, antihistamines.

  • Reasons fastcioleza
  • Symptoms fastcioleza
  • Diagnosis and treatment of fascioliasis
  • Prediction and prevention of fascioliasis
  • Fascioliasis - treatment

  • Fascioliasis


    helminthiasis, caused by parasitizing in the parenchyma of the liver and biliary tract or liver giant Fasciola (fluke). Along with opisthorchiasis, clonorchiasis, Paragonimiasis, schistosomiasis, fascioliasis of the most common human trematodozov. Fasciolosis caused by liver fluke, distributed in Australia, Europe and South America; fascioliasis associated with the trematode giant, found in Africa, Asia, parts of Central Asia and Transcaucasia. Described as sporadic and widespread outbreaks of disease covered by hundreds of people. According to available data, fascioliasis struck from 2.5 to 17 million. The world's population.

    cholangitis. General toxic effect on the body when fascioliasis due to blood entering the waste products of worms and liver tissue decay. At the end of a long course of fascioliasis can develop cirrhosis and portal hypertension.

    Fever may be low grade or high (up to 39-40 ° C), wear remitting or wavy character. Against this background, there is urticaria and pruritus, angioedema, high (80-85%), eosinophilia in the blood. Develop dyspepsia: nausea, vomiting, epigastric pain and right upper quadrant; there is an increase in liver size, accompanied by jaundice. In the early period often develop allergic myocarditis characterized by retrosternal pain, hypertension, tachycardia. After a few weeks of the clinical manifestations of acute fascioliasis significantly or completely subside.

    After 3-6 months, the disease enters the chronic stage, the symptoms of which are caused by direct liver disease and biliary tract. The course of chronic fascioliasis accompanied by hepatomegaly, paroxysmal pain in the right side; in periods of exacerbation - jaundice. Prolonged invasion leads to the development of dyspeptic syndrome, anemia, hepatitis, cirrhosis of the liver. Secondary infection is fraught with the appearance of purulent cholecystitis and cholangitis, abscesses of the liver, biliary tract stricture. The literature describes anecdotal cases of fascioliasis with atypical localization of flukes in the brain, lung, breast, eustachian tubes, larynx, subcutaneous abscesses.

    physician or gastroenterologist. A presumptive diagnosis is based on a set of epidemiological data, and clinical data. In favor of fascioliasis it indicates the presence of the previously reported cases of infection in a given territory, group morbidity, eating lettuce plants, drinking water from open sources or use it for washing dishes, fruits, vegetables and so on. In the early period of fascioliasis diagnosis is confirmed by serological methods (IFA ELISA, RIGA, RSK). In the chronic stage informative detection of Fasciola eggs in the feces or duodenal contents. Also parasites can be detected by ultrasound of the liver and gallbladder, liver CT. In biochemical assays marked increase in liver transaminases and alkaline phosphatase, hypoproteinemia, hypoalbuminemia. Fasciolosis be distinguished from opisthorchiasis, clonorchiasis, viral hepatitis, pancreatitis, cholangitis, cholecystitis other etiologies.

    fascioliasis treatment is carried out permanently. In the acute phase is assigned to light diet, desensitizing agents; the development of myocarditis and hepatitis shown glucocorticosteroids. To pass antiparasitic therapy only after decrease in acute phenomena. As etiotropic drugs in fascioliasis used triclabendazole, geksahlorparaksilol, praziquantel. For the purpose of the expulsion of the victims of Fasciola bile duct appointed cholagogue. Control parasitological examination (feces analysis on helminth eggs, duodenal intubation with the study of bile portions) is conducted at 3 and 6 months. In the case of suppurative complications require treatment with antibiotics and surgical intervention (drainage of liver abscess, drainage of the bile ducts, etc.).

    Prediction and prevention of fascioliasis



    Early diagnosis of fascioliasis allows for timely treatment and achieve recovery. At high intensity of infection or secondary bacterial infection prognosis can be serious, including death. Individual prophylaxis of fascioliasis is to prevent the use of raw water from reservoirs, poorly washed green stuff. public control measures include cleaning of reservoirs, protecting them from fecal contamination, elimination of the intermediate host of fascioliasis - molluscs, veterinary examination and deworming of cattle, health education.