Manganotti Cheilitis - Causes, Symptoms, Diagnosis and Treatment
Cheilitis Manganotti - Obligatny precancer red border of the lips. The disease occurs to form one or more painless erosions irregularly shaped with irregular edges. Erosive surface is covered with bloody crusts, when you try to remove that bleeding occurs. Cheilitis Manganotti Diagnosis is based on the basis of patient complaints, anamnesis, physical examination findings and laboratory studies. In identifying precancer obligatnogo pokazany rehabilitation and correction of hygienic condition of the oral cavity. Locally appointed keratoplasty, in the absence of positive dynamics of the pathological focus to be surgical excision.
Cheilitis Manganotti
Manganotti dermatologist, after whom got its name. Manganotti cheilitis detected mainly in people over age category. The main group of patients are male smokers older than 50 years, most of which is associated with a disease and topography with recurrent ulcers Herpes labialis, trauma to (biting) of the affected area. When Haley Manganotti erosion is often localized at the lateral portion of the lower lip. The need for additional testing to confirm the diagnosis occurs in 53% of patients. Among the total number of diseases RBCU prevalence of cheilitis Manganotti is 0.6%, whereas the rate of precancer diagnosis obligatnogo red border for workers non-ferrous metals, in contact with chemicals, reaches 16%.
herpes infection. Contributing factors in the development of cheilitis Manganotti are trophic age-related changes of tissues of the lower lip, smoking, nesanirovannaya mouth, disturbance of the functioning of the digestive system organs, vitamin deficiencies.
Microscopically at Hale Manganotti on the red border of the lips reveal the destruction of land with lack of epithelium in the center and the preservation of the epithelial layer on the periphery. The epithelium at the border with the surrounding tissues determine the signs of acanthosis. The stroma grow into long strands consisting of spinous cell layer. Also, in the deeper layers (basal and spinosum) on the periphery of the affected area is observed diskompleksatsiya cells. When Haley Manganotti in the underlying connective tissue exhibit inflammatory infiltrates - clusters of lymphocytes, macrophages and plasma cells. The surrounding tissues show signs of parakeratosis.
histological examination. As a rule, Hale Manganotti patients complain of initial or periodic appearance on a lip, at least a few painless erosions. On examination, the dentist finds in the red border of lips lesion, located within the epithelium. Fireplace red, irregularly-shaped, jagged edges with a diameter of 1 cm. The bottom is covered with serous or bloody crusts, erosion in the separation which is bleeding. Regional lymphadenitis with Haley Manganotti not diagnosed. Cytology smear is performed in order to exclude a possible malignancy erosive surface. Detection of cancer cells confirms malignancy Manganotti cheilitis.
Of key importance in the diagnosis are the results of histology. In the study of material obtained during surgery, when Hale Manganotti identify signs of acanthosis of the epithelium at the periphery of the erosion, epithelial defect in the heart. The underlying stroma detect clusters of lymphocytes, plasma cells. The surrounding tissue is present parakeratosis phenomena. Differentiate cheilitis Manganotti with pemphigus, erythema multiforme exudative, destructive forms of leukoplakia and lichen planus, herpes infection. The survey was conducted dental therapist. With the ineffectiveness of conservative therapy the patient is directed to consult a dental surgeon for subsequent excision of the lesion site.
removal of dental plaque, the treatment of caries and its complications. Vitamins A group administered oral as well as applications to the affected area. To improve the immune status, accelerate the recovery process is shown multivitamin complexes, which include thiamine, riboflavin, niacin.
During treatment patients cheilitis Manganotti prohibit sun exposure, smoking, eating spicy, spicy, hot food. In the case of ulcer surface infection in dentistry ointments based antimicrobials. In the absence of positive dynamics of conservative therapy cheilitis Manganotti lesion site was removed within healthy tissue surgically. Operative method of treating a disease is the most effective. With early treatment of patients with cheilitis Manganotti favorable prognosis. Late diagnosis of the disease leads to malignancy erosive surface.