Calluses on the feet may indicate dangerous

Can a hard skin on our feet to be a sign of cancer? Scientists have discovered a link between corn and cancer of the esophagus.

Calluses on the feet are traditionally perceived as harmless, though rather unpleasant consequences greater mobility and physical activity. There are many popular ways to combat calluses, but according to a new study, hard skin on the soles of the feet can be the result of a much more serious health problems. Scientists believe they have discovered a link between calluses on the feet, and cancer of the esophagus.

Researchers from Queen Mary University in London found that the hereditary form of thickening of the skin called keratoderma (tilez) says the risk of esophageal cancer. In some cases, tilez takes pronounced process that people have to cut the hardened areas of the skin with a razor blade. It figures out what is the cause of this disorder iRHOM2 gene plays an important role in the process of hardening of the skin of the palms and soles, because it controls the keratin - the most abundant component in the level of the skin.

The researchers found that mice with the deleted gene iRHOM2 had abnormally thin skin on the legs. While a person with a high content iRHOM2 demonstrates thicker skin of the feet and hands with calluses, it is more often faced with esophageal cancer. The results of this study may lead to new directions in the development of treatments for cancer of the esophagus, as well as radically new understanding of disorders such as psoriasis and skin cancer.