Bowenoid papulosis - A sexually transmitted disease caused by the human papillomavirus, which manifests itself erythematous patches, papules or plaques and proceeding with genital skin lesions, perineum, perianal region or thighs. Bowenoid papulosis refers to precancerous skin condition. Diagnosis bovenoidogo papulosis is based on the clinical picture, PCR detection of human papillomavirus negative serological tests for syphilis, the results of histological examination. Treatment Bowenoid papulosis is to carry out a total of antiviral therapy and removal of skin cells by laser, electrocoagulation, excision or cryodestruction.
Bowen's disease. Then it was revealed his relationship with the human papilloma virus. Disease Bowenoid papulosis susceptible men and women, mostly aged 17-40 years. In clinical Venereology also observed some cases of Bowenoid papulosis in children, including newborns whose mothers had the disease.
Bowenoid pappulez - a relatively rare disease. Recently, however, a trend towards an increase in the number of cases, which is associated with an increase in promiscuity in society.
warts, warts and papillomas. Most of the authors shows the connection of the disease with HPV 161831 33 types. Some studies indicate that detection of patients with Bowenoid papulosis and other types of HPV.
Infection Bowenoid papulosis, like other sexually transmitted diseases (gonorrhea, syphilis, chlamydia, ureaplasmosis etc.) Are sexually transmitted. The incubation period can take anywhere from 2-3 months to several years.
leukoplakia plaques. Elements can have multiple or single character size from a few millimeters up to 3-3.5 cm. Usually they are not accompanied by subjective feelings, in some cases, patients complain of itching. With the development of inflammation appears soreness.
Pigmented papule Bowenoid papulosis are red-brown, pink, purple or yellow in color. Their consistency testovatoy, the surface is usually smooth, sometimes warty. Lichenoid papules Bowenoid papulosis is a local thickening of the skin with power and rough skin pattern. They are more likely to have normal skin color and rough surface may be coated with serous crusts. The individual papules merge together to form plaques. Leykoplakiepodobnye plaque painted in milky white or grayish-white color, their edges are clearly distinguished from healthy skin.
The most typical arrangement of elements Bowenoid papulosis in men on the penis, women - on the clitoris and labia. Available localization in the groin, skin thighs and perineum, around the anus, on the mucous membrane of the mouth and pharynx. As a rule, on the trunk of the penis in men, in the area of the vulva and around the anus in women observed pigmented papules on the glans penis - lichenoid.
Along with manifestations Bowenoid papulosis patients often have warts and genital warts. In women, there is a combination Bowenoid papulosis with cervical dysplasia.
For Bowenoid papulosis is characterized by long duration of progression-free process with periods of spontaneous remissions. In some cases there was spontaneous resolution of the disease. However, despite the seeming harmlessness Bowenoid papulosis, it refers to precancerous skin diseases. Always there is the possibility of transformation of its elements in squamous skin cancer, genital Bowen's disease, cancer of the penis in men and vulval cancer in women. In connection with these patients with Bowenoid papulosis should consist in the dispensary at venereologist or dermatologist and undergo regular check-ups.
consulting a gynecologist, urologist or andrologist. In such cases, the patient is directed to venereal diseases, which establishes the diagnosis based on clinical data, results of PCR diagnostics, cytological and histological examination of material obtained from the affected area of the skin.
The analysis is focused on the identification and typing of Human Papillomavirus. They are carried out by scraping, the patient's blood or swabs taken from the genitals. To exclude a syphilitic nature of skin cells is carried out their research at the pale treponemu, serological diagnosis (RPR-test RIBT, RIF).
Scraping cytology or smears elements Bowenoid papulosis koilocytosis reveals the presence of - a large number of epithelial cells with characteristic enlightenment around the nucleus, as well as cells with double nuclei. Histology Bowenoid papulosis corresponds cancer in situ. There has been the proliferation of keratinocytes and atypical mitosis. Specific Bowenoid papulosis polymorphic atypical cells with hyperchromatic nuclei diffusely scattered over the entire thickness of the epidermis, while Bowen's disease these cells are arranged in compact groups.
Differential diagnosis Bowenoid papulosis conducted with syphilis, genital warts, psoriasis, lichen planus, Bowen's disease, common warts.
Treatment Bowenoid papulosis
The need for treatment Bowenoid papulosis is dictated by its probability of malignancy. Produced cryosurgery, laser ablation, electrocautery or surgical excision elements Bowenoid papulosis. It is used as the application of cytostatics (prospidiya chloride, fluorouracil) to the affected areas of the skin or obkalyvanie interferon. Local treatment Bowenoid papulosis accompanied total antiviral therapy.
Note that Bowenoid papulosis prone to frequent recurrence and even its complete treatment is not always effective enough.
Prevention Bowenoid papulosis
Measures aimed at the prevention of infection with the development Bowenoid papulosis, the general principles of STI prevention. These include primarily reasonable sexual behavior and condom use during sexual intercourse.